Mark Goulian

My lab is broadly interested in the mechanisms bacteria employ to adapt to changes in their environment. Most of our efforts have focused on the biochemical circuits that enable Escherichia coli and related bacteria to sense and respond to intra- and extracellular cues. We are especially interested in how these circuits function, evolve and interact with other pathways in the cell. Current research interests include adaptation to changes in the availability of oxygen or other nutrients, bacterial phosphohistidine phosphatases, and commensal colonization of animal hosts.