Biology is fundamental to our changing world. The 21st century challenge for our students, our scholars, and the greater society is to understand our place in this changing world and to create fundamental knowledge for informed policies, economies, and social structure.
Siberian Larch, taken at our field site near Lake Khovsgol in north-central Mongolia. We are analyzing tree-ring width and stable isotopes of the tree rings to reconstruct climate, and Larch responses to climate change, over the past century as the temperature in Mongolia has risen.
ERK1/2 signaling pathway regulates exocytosis and tumor invasion through phosphorylation of the exocyst complex.
Pupa of the butterfly Porphyrogenes peterwegii "peering" out of its leafy nest with false eyes, which in turn mimic the eyes of a snake, thereby protecting the pupa from small feather-brained birds.
Malaria parasites (and their kin) can be viewed as minimal eukaryotes, harboring a nucleus (yellow), a secretory pathway the Golgi (purple) and specialized ‘rhotpry’ organelle (black), and two endosymbiotic organelles, the mitochondrion (red) and apicoplast (green).
Many genes that organisms use to regulate their mutualists are also used to defend against parasites and pathogens. The shared genetic control of beneficial and harmful symbioses raises the intriguing possibility that susceptibility to infection is a pleiotropic cost of mutualism. Our goal is to understand how a genetic tradeoff between attracting mutualists and repelling parasites has shaped the genomic architecture of traits mediating species interactions, and how ongoing conflict influences adaptation.