Event

The Lechtreck lab (https://research.franklin.uga.edu/Lechtreck-Lab/) explores how cells construct, maintain and utilize cilia, including studies on microtubule-based intraflagellar transport, length control and mechano-sensation.  Much of their work exploits the unicellular alga Chlamydomonas reinhardtii, as a genetically accessible model system for investigating all manner of ciliary biology.

• Liu P et al 2020.  Chlamydomonas PKD2 organizes mastigonemes, hair-like glycoprotein polymers on cilia.  J Cell Biol 219:e202001122  doi:10.1083/jcb.202001122.
• Craft van de Weghe J et al 2020.  Diffusion rather than intraflagellar transport likely provides most of the tubulin required for axonemal assembly in Chlamydomonas.  J Cell Sci 133:jcs249805  doi:10.1242/jcs.249805.
• Dai J et al 2018.  In vivo analysis of outer arm dynein transport reveals cargo-specific intraflagellar transport properties.  Molec Biol Cell 29:2553-65  doi: 10.1091/mbc.E18-05-0291.
• Craft JM et al 2015.  Tubulin transport by IFT is upregulated during ciliary growth by a cilium-autonomous mechanism.  J Cell Biol 208:223-37  doi:10.1083/jcb.201409036.

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