Cancer's tricks

Wei Guo of the School of Arts & Sciences and colleagues from the Perelman School of Medicine, School of Veterinary Medicine, and School of Engineering and Applied Science have teamed up to uncover how solid tumors manipulate cancer-fighting CAR T cells through extracellular vesicles. This causes the engineered CAR T cells to commit fratricide, essentially turning against each other instead of attacking the cancer.

BIOL3851 - Biology and Society (SNF Paideia Program Course)

Status
A
Activity
SEM
Section number integer
301
Title (text only)
Biology and Society (SNF Paideia Program Course)
Term
2025C
Subject area
BIOL
Section number only
301
Section ID
BIOL3851301
Course number integer
3851
Meeting times
R 3:30 PM-6:29 PM
Level
undergraduate
Instructors
Haider Manzer
Description
This course uses a biological foundation to explore general issues at the interface of biology and society. We will use both historical and contemporary reading materials, with an emphasis on the primary scientific literature, to inform discussions on often controversial issues in biology as well as the social responsibility of scientists to respond to these issues. The course will cover how science has shaped social and political opinions on such topics as race, ethnicity, and gender, as well as how society and politics are influenced by and impact science. This course will provide a background and context in which to consider, anticipate, and respond to biology's present and future ethical and social implications.
Course number only
3851
Use local description
No

Marcelina Martynek awarded Penn Global Dissertation Grant

The Penn Global Dissertation Grants program is designed to enhance global components of dissertation research for the graduate student community. In partnership with the Vice Provost for Education, this program awards up to $8,000 to selected Ph.D. candidates to broaden their international dissertation research and leverage opportunities for careers in global leadership. This is the second year of the program, after a successful launch in 2024.

BIOL5024 - Cell Motility and the Cytoskeleton

Status
A
Activity
SEM
Section number integer
401
Title (text only)
Cell Motility and the Cytoskeleton
Term
2025C
Subject area
BIOL
Section number only
401
Section ID
BIOL5024401
Course number integer
5024
Meeting times
MW 3:30 PM-4:59 PM
Level
graduate
Instructors
Tatyana M. Svitkina
Description
Cytoskeleton and cell motility plays a crucial role in many aspects of normal and pathological physiology of individual cells, tissues, and whole organisms, including morphogenesis, immune response, wound healing, oncogenesis, and infection. This course will cover current topics in cell biology with emphasis on cytoskeleton and cell motility and their roles in these processes. Lectures, student presentations, and discussions in the class will be based on primary scientific literature.
Course number only
5024
Cross listings
BIOL4024401
Use local description
No

BIOL5262 - Biological Foundations for Bioengineering and Biotechnology: Genomics and Omics Technologies

Status
A
Activity
LEC
Section number integer
1
Title (text only)
Biological Foundations for Bioengineering and Biotechnology: Genomics and Omics Technologies
Term
2025C
Subject area
BIOL
Section number only
001
Section ID
BIOL5262001
Course number integer
5262
Meeting times
MW 3:30 PM-4:59 PM
Level
graduate
Instructors
Alex Harris
Description
This course is designed for students in graduate level degree programs with an interest in developing a strong understanding of core concepts in genetics and omics technologies. It is assumed that students either have familiarity with undergraduate level biology topics, or can quickly catch up to keep pace with the course. We will focus on genetics, genomics, and bioinformatics topics ranging from transcriptomics to transgenic organisms to epigenetics. This fast-paced course will cover both foundational principles, as well as modern applications and developments, offering hands-on active learning opportunities where possible. Students will be expected to engage deeply with the material, and will have the opportunity to develop scientific skills in critical thinking, reading, and communication, culminating in a final group presentation at the end of the semester. Upon completion of the course, students should feel empowered to enroll in any advanced genetics/genomics-based biology course at Penn.
Course number only
5262
Use local description
No

BIOL7000 - Advanced Topics in Current Biological Research

Status
A
Activity
SEM
Section number integer
301
Title (text only)
Advanced Topics in Current Biological Research
Term
2025C
Subject area
BIOL
Section number only
301
Section ID
BIOL7000301
Course number integer
7000
Level
graduate
Instructors
David S. Roos
Description
Integrative seminar on current biological research for first-year PhD students.
Course number only
7000
Use local description
No

BIOL5860 - Mathematical Modeling in Biology

Status
X
Activity
LEC
Section number integer
401
Title (text only)
Mathematical Modeling in Biology
Term
2025C
Subject area
BIOL
Section number only
401
Section ID
BIOL5860401
Course number integer
5860
Meeting times
CANCELED
Level
graduate
Instructors
Toshiyuki Ogawa
Description
This course will cover various mathematical models and tools that are used to study modern biological problems. Mathematical models may be drawn from cell biology, physiology, population genetics, or ecology. Tools in dynamical systems or stochastic processes will be introduced as necessary. No prior knowledge of biology is needed to take this course, but some familiarity with differential equations and probability will be assumed.
Course number only
5860
Cross listings
MATH5861401
Use local description
No

BIOL5825 - Biochemistry and Molecular Genetics Superlab

Status
A
Activity
LAB
Section number integer
401
Title (text only)
Biochemistry and Molecular Genetics Superlab
Term
2025C
Subject area
BIOL
Section number only
401
Section ID
BIOL5825401
Course number integer
5825
Meeting times
TR 1:45 PM-4:44 PM
Level
graduate
Instructors
Jennifer A Punt
John D Wagner
Description
Intensive laboratory class where open-ended, interesting biological problems are explored using modern lab techniques. Topics may include protein structure/function studies; genetic screens, genomics and gene expression studies; proteomics and protein purification techniques; and molecular cloning and DNA manipulation. The course emphasizes developing scientific communication and independent research skills. Course topics reflect the interests of individual Biology faculty members. This course is recommended for students considering independent research.
Course number only
5825
Cross listings
BIOL4825401
Use local description
No

BIOL5820 - Biological Foundations: Exploring Groundbreaking Research

Status
A
Activity
SEM
Section number integer
301
Title (text only)
Biological Foundations: Exploring Groundbreaking Research
Term
2025C
Subject area
BIOL
Section number only
301
Section ID
BIOL5820301
Course number integer
5820
Meeting times
MW 12:00 PM-1:29 PM
Level
graduate
Instructors
Alex Harris
Description
Designed for graduate students with an interest in exploring important discoveries in the biological sciences through the lens of literature discussion. We will emphasize work that has won the Nobel Prize in Physiology or Medicine, and its relevance to modern research. It is assumed that students have familiarity with undergraduate biology topics, or can catch up, to keep pace with discussions. In addition to instructor-guided exploration of course material, students will be expected to lead journal club-style discussions on papers of their choosing. Upon successful completion of this course, students will have both a greater appreciation for major discoveries in the biological sciences, and a greater ability to discuss and apply these discoveries to their own scientific questions.
Course number only
5820
Use local description
No