The course will focus on muscle function from the level of molecules to whole animal locomotion. At each level of organization, muscle function will be explored from mechanical and energetic viewpoints. The course will include lectures, demonstrations, and several guest expert lectures. Students will also be introduced to realistic musculo-skeletal modelling and forward dynamic simulations to explore integrated function.

This course is designed for advanced undergraduate and graduate students who are interested in molecular physiology of sensory signal transduction. The major topics to cover will be signal transduction mechanisms used by membrane ion channels and receptors that detect the sensory stimuli (light, sound, temperature and taste, for example) and transmit the signals to the nervous system. Modern molecular/structural techniques (patch clamp, protein crystallization, molecular genetics, expression cloning and protein purification) will be introduced along with each topic. References will be primary research articles. Students will critically evaluate research discoveries by reading and presenting one to two original research papers. Each student is required to write a 10-page research proposal and to critique proposals written by fellow students.

The course will examine major sources of energy on earth: sunlight, mechanical, chemical and biological, and how this energy is transformed into useful energy for humans -- typically electrical energy, heat, mechanical power or food. Considerable emphasis will be on forms of regenerative energy that can be used when living off-the-grid. As a case study, we will examine some approaches taken by the US military to provide energy capability for dismounted Marines operating on foot in austere environments. Faculty lectures will be supplemented by guest lectures from leaders in various areas of science. A major goal of the course is for students to develop an awareness of the amounts of energy they use in their daily lives, and how they might reduce them. As an exercise, students will measure how much energy their smart phones and laptops use in a day and try to generate a comparable amount of energy through physical effort. The course will include lectures, discussion, guest expert lectures, and laboratory measurements.

This course will be a focused study of genomes, genomic techniques, and how these approaches are and will be used in diagnosing and treating human disease. Topics will include genome sequencing, analysis of sequences and microarrays, and new techniques including high-throughput sequencing and reverse genetic analysis with a focus on genome-wide mutant collections. Prerequisite: BIOL 421 strongly recommended.

Intensive laboratory class where open-ended, interesting biological problems are explored using modern lab techniques. Topics may include protein structure/function studies; genetic screens, genomics and gene expression studies; proteomics and protein purification techniques; and molecular cloning and DNA manipulation. The course emphasizes developing scientific communication and independent research skills. Course topics reflect the interests of individual Biology faculty members. This course is recommended for students considering independent research.

Introduction to basic theoretical tools to study the evolutionary and ecological dynamics of populations. Topics to be discussed include: basic population dynamics and population genetics theory, evolutionary game theory/adaptive dynamics, social evolution (kin selection/multilevel selection), life-history evolution, and stochastic models. Other topics may be added based on the specific interests of students in the class.

Survey of the physical, chemical and biological properties of freshwater ecosystems, both riverine and lentic, natural and polluted. Prerequisite: One semester of college chemistry.

This course will focus on the molecular mechanisms by which fundamental cellular processes are disrupted in the development of cancer.

This course is designed for advanced undergraduates and beginning graduate students with a particular interest in infectious disease biology. Note that this course is not a comprehensive survey of the field and is not appropriate for students seeking a lecture course on disease. The primary objective of this course is to teach students considering a career in the biomedical sciences how to read, discuss, and question research papers effectively. Intensive classroom discussions focus on the experimental methods used, results obtained, interpretation of these results in the context of pathogen interactions with host cells and organisms, and implications for basic research and therapeutic development. Prerequisite: BIOL 221 recommended.

Early development of microbiology, pathology, and immunobiology; molecular and cellular bases of immune phenomena including: immunity to pathogens, immune diseases, autoimmunity, and hypersensitivity. This course is open to students in the College of Liberal and Professional Studies only.